Washington: A new study suggests that 100 percent orange juice has the ability to help fight inflammation and oxidative stress in adults. The findings of the study were published in the journal ‘Advance in Nutrition’. Although its scope is limited, studies indicate that drinking 100 percent orange juice significantly reduces interleukin 6, a well-established marker of inflammation, in both healthy and high-risk adults.
Two additional inflammatory and oxidative stress markers were also reduced; However, the results did not quite reach statistical significance. The findings of this study, which was funded through an unrestricted grant by the Florida Department of Citrus, are in line with a previously published FDOC-funded review, which described the primary bioactive compounds found in oranges and in 100 percent orange juice. Beneficial effects of hesperidin were reported. Reducing certain markers of inflammation and oxidative stress.
Chronic inflammation can play an important role in causing or leading to certain chronic diseases, including heart disease and diabetes. “We know that 100 percent orange juice contains several nutrients, such as vitamin C, as well as beneficial bioactive compounds that have the ability to reduce inflammation and oxidative stress,” says Florida Department of Citrus registered dietitian Gail Rampersaud. he said.
“This review tells us that some studies find benefit with 100 percent orange juice, but we need more data and larger well-designed studies to draw more definitive conclusions. This analysis is particularly helpful. as we and others plan for future research related to orange juice,” added Rampersaud.
The review examined published studies relating to 100 percent orange juice and markers of inflammation and oxidative stress. The review was conducted by the Think Healthy Group and researchers from Tufts University and George Mason University.
The analysis consisted of three parts: a qualitative scoping review of 21 studies with a total of 307 healthy adults and 327 adults; a systematic review of a subset of 16 studies that measured the six most commonly reported biomarkers related to inflammation and oxidative stress in the body; and 10 studies that had enough data to conduct a meta-analysis.
The researchers also examined the overall quality and potential bias in the study. The widest scope and systematic reviews showed that, in general, 100 percent orange juice had beneficial or zero (no adverse) effects on oxidative stress or inflammation.
The researchers cautioned that the studies involved a relatively small number of subjects, had low strength of evidence, and had a moderate risk of bias; Therefore, the overall findings should be interpreted with caution.
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