New strain of Covid-19 found in France: more infectious than Omicron? We all know about the IHU version

New Delhi: With the rapid increase in the highly mutated Omicron variant of SARS-CoV-2 across the world, another new variant has emerged. Now, a new strain of the virus causing COVID-19 has been identified in southern France by scientists. Known as ‘IHU’, version B.1.640.2 has been reported in at least 12 cases by researchers at the Institute IHU Mediterranee Infection, and has been linked to travel to the African country of Cameroon. However, the researchers noted that as far as protection from infection and vaccines are concerned, it is too early to speculate.

The peer-reviewed study posted on the preprint repository MedRxiv on December 29 showed that IHU has 46 Mutations and 37 deletions resulted in 30 amino acid substitutions and 12 deletions. Amino acids are molecules that combine to form proteins, and both are the building blocks of life. Fourteen amino acid substitutions, including N501Y and E484K, and nine deletions are located in the spike protein. Most of the vaccines currently in use target the spike protein of SARS-CoV-2, which the virus uses to enter and infect cells. The N501Y and E484K mutations were also previously found in beta, gamma, theta and omicron variants.

“The mutation set and phylogenetic position of the genome obtained here points to a new variant called IHU based on our previous definition,” said the study’s authors.
“These data are yet another example of the unpredictability of the emergence of SARS-CoV-2 variants and their introduction into a geographic area from overseas,” he said.

B.1.640.2 has not yet been identified in other countries or labeled a variant under investigation by the World Health Organization (WHO).

According to the researchers, the index (first) case was an adult diagnosed positive by RTPCR carried out in a laboratory on a nasopharyngeal sample collected in mid-November last year. Epidemiologist Eric Feigl-Ding posted a lengthy Twitter thread in which he said that new variants keep coming out but that doesn’t mean they will be more dangerous. “What makes a variant more famous and dangerous is its ability to multiply due to the number of mutations that occur in relation to the original virus,” Feigl-Ding tweeted on Tuesday. “This is when it becomes “a sort of worry” — like Omicron, which is more infectious and more immune to the past. It remains to be seen what category this new variant will fall into,” he said. said.

Several countries are currently experiencing a spike in COVID-19 cases driven by the Omicron variant, which was first identified in South Africa and Botswana in November last year. Since then, the form of concern has spread to more than 100 countries. In India, a total of 1,892 cases of Omicron type have been detected in 23 states and union territories so far.

Here’s what we know about IHU in a nutshell:

• Researchers say that there are 46 mutations in it. it’s more than that omicron, which can make it contagious and more resistant to vaccines. However, it is yet to be studied.
• Around 12 cases have been identified so far near Marseille, the first of which is linked to travel to the African country of Cameroon.
• 14 amino acid substitutions, including N501Y and E484K, and nine deletions are located in the spike protein. The N501Y and E484K mutations were also previously found in beta, gamma, theta and omicron variants.
• So far, it has not been observed in any other country and has not been labeled a variant under investigation by the World Health Organization.

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