New Delhi: A new study finds that COVID-19 vaccines are effective in reducing serious illnesses that require hospitalization, and that breakthrough infections are almost twice as likely to be completely asymptomatic after two doses. it occurs.
The occurrence of SARS-CoV-2 infection after vaccination has been described as a successful infection. The study sheds light on the characteristics of post-vaccination disease and says that after two shots of any COVID vaccine, the chances of hospitalization are reduced by more than two-thirds.
The study has been carried out extensively by researchers from several universities in the United Kingdom. published In The Lancet Infectious Disease Journal.
The researchers also found that the likelihood of experiencing tall covid The condition when the illness lasted 28 days or more after a positive test was reduced to half for people taking two doses.
The study was conducted on UK users of the ZOE Covid Study app.
However, the report noted that since the data obtained from the app was self-reported, comorbidities, vaccination status and test results could be inaccurate, and people living in disadvantaged areas could be under-represented.
less that 0.2% tested positive after the second shot
The study was conducted between December 8, 2020 and July 4, 2021, and participants reported their status of COVID-19 infection and vaccination via the ZOE app as part of the UK COVID Symptom Study.
12,40,009 users reported that they had received the first vaccine dose, and 6,030 of them, or less than 0.5 percent, subsequently tested positive for SARS-CoV-2 (case 1). 9,71,504 users reported taking a second dose, and 2,370, or less than 0.2 percent, tested positive for COVID-19 (case 2). More than 1.2 million adults had received at least one dose of the Pfizer-BioNtech, Oxford-AstraZeneca or Moderna vaccines.
The odds of a breakthrough infection being asymptomatic increased by 63 percent after the first dose, and by 94 percent after the second dose.
There was a 50 percent reduction in people experiencing long-term covids compared to those receiving both doses. Also, the odds of having severe illness, that is, the likelihood of suffering five or more symptoms in the first week of illness, was reduced by 70 percent.
Vulnerable adults (60 years and older) were among those most vulnerable to breakthrough infection after the first dose. Other vulnerable people were adults with underlying health conditions such as kidney disease, heart disease, obesity and lung disease. Living in disadvantaged areas, including densely populated urban areas, was a common factor across all age groups determining a greater likelihood of experiencing a successful transition.
‘Vaccines are doing exactly what they were designed to do – save lives’
Communities with lower vaccination rates overall and closer living quarters were more likely to spread the virus. These factors were mostly related to cases of infection after the first shot and before the second dose.
Unvaccinated people suffer from fatigue, cough, fever and loss of taste and smell more often than those who have received at least one dose of vaccination.
One of the study’s lead authors, Dr. Claire Steves from King’s College London, UK, said: “We are at a critical point in the pandemic as we see cases increasing worldwide due to the delta variant. Conclusive infections are expected. And don’t underestimate the fact that these vaccines are doing exactly what they were designed to do – save lives and prevent serious disease.”
She said: “Other research has shown the mortality rate for hospitalized COVID-19 patients to be up to 27%. We can greatly reduce that number through vaccination by keeping people out of the hospital in the first place. Our findings play an important role in larger efforts to prevent COVID-19 infection, which should still include other personal protective measures such as wearing masks, frequent testing and social distancing. “
Study co-author Dr. Ross Penfold said older age groups who are vulnerable and living in care homes, people living in disadvantaged situations, and people with underlying health conditions were at greater risk of exposure and more vulnerable to infection. were sensitive. From SARS-CoV-2.
These groups should be prioritized and informed about the time between first and second doses and potential booster doses with the help of specially designed health policies, the statement said.
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