The third ongoing trial of MACH-19 measures whether the same medicinal mushrooms, which were given in capsules at the time of initial COVID vaccination, can increase antibodies and other measures of immune response.
The fourth trial, yet to be launched, will see whether medicinal mushrooms can provide a similar lift to Covid-19 booster shots as an adjuvant, a substance that boosts the immune response.
“Vaccines lead to the production of antibodies that can destroy the virus in the blood,” Saxe said.
“Mushrooms may not only increase the number of these antibodies, but may also enhance T-cell immunity against virally infected cells. In addition, because mushrooms bind to receptors on human immune cells, they may modify our immunity. Can – it can increase and calm down in some ways. It is down in others and this property of mushroom can also reduce side effects related to vaccine.
Naturopathy has been used to treat infectious diseases for centuries, according to Sachs, who noted that the herb helped Chinese doctors manage 300 recorded epidemics, while the Greek pharmacologist Pedanius Dioscorides prescribed agaricon for the treatment of pulmonary infections 2,300 years ago.
The three trials under MACH-19, two of which are Food and Drug Administration (FDA)-approved, are currently enrolling for 66 to 80 patients who have tested positive for SARS-CoV-2 and who are mild. from home quarantine. Moderate symptoms. Preliminary safety data from the trials are expected by the end of this year, with efficacy data ready within a year.
Inputs from IANS
,