ZyCOV-D is a COVID-19 vaccine developed and manufactured by Zydus Cadila, a leading Indian pharmaceutical manufacturer, to fight the novel coronavirus.
The vaccine, which was pressed into clinical trials last July, is likely to be the third Indian coronavirus vaccine to be launched for use. The vaccine is not only a vaccine manufactured in India, but it is also the first of its kind coronavirus vaccine that uses a DNA platform to elicit an adequate immune response.
ZyCOV-D is a ‘plasmid DNA’ vaccine that uses a non-replicating version of a DNA molecule called a plasmid, coded with genetic information similar to mRNA vaccines, to produce a harmless version of the spike protein present on SARS. Helps to – COV-2 membrane.
Once the vaccine is injected into the body, the plasmid DNA elicits an immediate response that mimics spike protein production, ejects antibodies, and signals a defensive response if future infections are observed. .
The company, which claims to be conducting one of the largest COVID vaccine clinical trials in Indian centers, has just sought clinical permission for regulatory use in children aged 12-18 years. Once approved for use, the company plans to rapidly ramp up production and manufacture 10-12 crore doses annually.
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