As estimates on the efficacy of mixing COVID-19 vaccines coronavirus The Subject Expert Committee (SEC) of the Central Drugs Standard Control Organization (CDSCO) has continued to change and evolve, telling CNN-News that it favors giving people separate doses of Covaxin and Covishield.
This will be the first mix and match study in India of two indigenous vaccines, which will be clinically conducted by Christian Medical College (CMC) in Vellore.
Mixing and matching coronavirus vaccine shots refers to the process of administering one brand of vaccine for the first dose and using a vaccine made by a different vaccine manufacturer for the second dose. As the delta version of the coronavirus continues to spread rapidly around the world and re-emerge, reducing the efficacy rate of available vaccines, experts believe that at such a critical stage, two vaccines may be needed. Mixing, or selecting different doses of vaccines can potentially trigger higher efficacy, effectiveness, and immunity and reduce any safety concerns that may be present with some vaccines.
The mix-and-match strategy is known as heterogeneous prime and boost and has been used in the past against diseases such as Ebola and AIDS.
As India gears up for its first mix and match study, here is a look at some of the countries that have already allowed a mix of the two vaccines.
Canada
The North American country decided to vaccinate beneficiaries who have already received a single dose of the AstraZeneca vaccine along with another shot from Pfizer or Moderna. In a similar decision, the National Advisory Committee on Immunization also allowed beneficiaries who have been given the first dose of Pfizer or Moderna to accompany someone during their second dose. The lack of a Kovid vaccine has also met this need.
America
On June 1, the US became the latest country to announce the start of clinical trials to test the use of various COVID vaccines in fully vaccinated adults as a booster shot. The test results are expected in late 2021.
UK
In January, the British government said that people can mix and match their two shots if they are unaware of the vaccine they have received, or the vaccine they received as their first dose is not available. They also allowed Pfizer and Moderna vaccines to be used interchangeably. An Oxford-University-led study found that beneficiaries who were vaccinated with two different vaccines were more likely to suffer mild or moderate post-vaccination illnesses than those vaccinated with the same dose. More likely.
United Arab Emirates
The United Arab Emirates has made the Pfizer/BioNTech coronavirus vaccine available as a booster shot, initially immunizing against the vaccine developed by the China National Pharmaceutical Group (Sinopharm).
Spain
In May, the Spanish government allowed beneficiaries who have been vaccinated with the AstraZeneca vaccine to opt for the Pfizer vaccine as their second dose. However, permission was given only to adults under the age of 60. Spain’s government said its decision was supported by a trial conducted by the Carlos III Health Institute, which found that Pfizer’s second dose, after AstraZeneca, was highly effective and safe.
Bahrain
Bahrain said on June 4 that eligible candidates could receive a booster shot of either Pfizer/BioNTech (PFEN) or SinoPharm vaccine, regardless of the shot they initially took after seeing a spike in Covid cases on the island.
In addition to these, France, Norway and Sweden have also allowed those taking a single dose of the AstraZeneca vaccine to take one of the approved mRNA vaccines as their second dose.
Countries still considering mixing the two vaccine doses include Russia and South Korea. According to sources, the Chinese government is also conducting studies and clinical trials before taking a decision on the issue. Russian health officials have now asked for more clinical data and withheld the decision after granting initial approval for a mixture of Sputnik V and AstraZeneca supplements. France’s top health advisory body recommended in April that people under the age of 55 who are first injected with AstraZeneca should receive a second dose with the so-called messenger RNA vaccine, although doses-mixing in trials are yet to be evaluated. has not been done.
read all Breaking Newshandjob breaking news And coronavirus news Here
.