NEERI genome sequencing speedy, NIV results pending for more than a year. Nagpur News – Times of India

Nagpur: Though the district administration has decided to send 10 samples of COVID patients from the Umred family to the National Institute of Virology (NIV), Pune for genomic sequencing, the research body and two medical colleges have not been able to fast. Processing and distribution of results of earlier cases. This time too, the response has been normal with 10 samples being sent to the NIV by the Indira Gandhi Government Medical College and Hospital (IGGMCH) and the Government Medical College and Hospital (GMCH), which was assigned the task. District Collector.
On the other hand, CSIR-NEERI has already sent the sequencing quality RNA of eight Umred family samples, while two more family members who were found COVID positive later, were not shared with it. NEERI, conducting genomic sequencing in collaboration with the Center for Cellular and Molecular Biology (CCMB), Hyderabad, is ready to declare the results through the collector in a day or two.
Compared to the NEERI-CCMB study pace, no one knows the fate of the hundreds of samples sent by IGGMCH and GMCH Viral Research Diagnostics Lab (VRDL) since the outbreak of the pandemic.
As soon as the Collector requested Dr Krishna Khairnar, Head of Environmental Virology, Neeri Nagpur, his team took RTPCR samples and started sequencing them before sending them to CCMB.
Reportedly eight samples are still lying in IGGMCH while two are in GMCH. In December last year, both medical colleges left samples of UK strain suspects for more than two days. The sequencing results of UK-returned COVID positive were delayed by over 14 days by the NIV, which has workloads from across the country.
As the initial results are expected from NEERI, it will also come as a relief to the eight patients who have been kept in institutional quarantine at Umred COVID Care Centre.
Officials of both the medical colleges said that the NIV has never been prompt in taking samples or giving results. IGGMCH officials said that as per protocol, they are sending specific samples to NIV Pune every 15 days, but rarely have results. GMCH officials also said that initially they would seek the results but did not get any response.
Around 150 samples were sent to NCDC in New Delhi during the second wave from different parts of the city. The results of these were also not shared with the administrative authorities or the medical colleges.
Arguably, NEERI is perhaps the only center where a large number of samples have been taken for a single city. On the request of the then Divisional Commissioner Sanjeev Kumar, the principal research body and the CCM had sequenced 412 samples between October 2020 and May 2021.
The NEERI lab will send a batch of 100 samples to CCMB and get the results within 10 days. Contrary to confidentiality and denials by other institutions, NEERI submitted a detailed report to Kumar.
According to the report, NEERI, led by Dr Khairnar, was the first to report lineage B1.617.2 (double mutant) on SARS-Cov2 to the Indian SARS-CoV2 Genomics Consortium (INSACOG). genome sequencing. Later in May, this version was named Delta by the WHO. It was found that Delta is prevalent in more than 70% of positive patients.

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