New Delhi: The National Institutes of Health (NIH), a part of the US Department of Health and Human Services, said on Tuesday (June 29, 2021) that Covaxin ‘effectively’ neutralizes alpha and delta variants of COVID-19.
It cited two studies and said that they have found that the Covaxin coronavirus vaccine generates antibodies that neutralize the alpha and delta variants of COVID-19, First identified in the United Kingdom and India, respectively.
“Results from two studies of blood serum from people receiving Covaxin suggest that the vaccine produces antibodies that effectively neutralize the B.1.17 (alpha) and B.1.617 (delta) variants of SARS-CoV-2 , which was first identified in the United Kingdom and India, respectively,” the NIH said.
It is worth noting that Phase 2 trials of the vaccine indicate that it is safe and well-tolerated and there are unpublished interim results. Phase 3 trial indicates vaccine has 78% efficacy against symptomatic disease, 100% efficacy against severe COVID-19 including hospitalization, and 70% efficacy against asymptomatic infection with SARS-CoV-2.
Meanwhile, the National Institutes of Health also announced that an adjuvant developed with its funding has contributed to the success of ‘highly efficacious’ Covaxin. Adjuvants, specifically, are substances designed as part of a vaccine to boost the immune response and enhance the effectiveness of a vaccine.
According to the NIH, Covaxin, the adjuvant used in Alhydroxiquim-II, was discovered and tested in the laboratory by the biotech company ViroVax LLC of Lawrence, Kansas, with particular support from the NIAID Adjuvant Development Program.
“Ending a global pandemic requires a global response,” said Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH.
He added, “I am delighted that Adjuvant, a novel vaccine developed in the United States with NIAID support, is part of an effective COVID-19 vaccine available to people in India.”
It should be noted that Covaxin has been developed by Bharat Biotech in collaboration with the Indian Council of Medical Research, and is one of three vaccines currently administered across India.
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