Combining COVID vaccine doses may improve effectiveness against mutations, more data needed: Dr Guleria

amid fears that vaccines may be ineffective against different and more potent forms coronavirus Dr Randeep Guleria, Director, All India Institute of Medical Sciences (AIIMS) has suggested that combining the doses of two different vaccines can improve their efficacy against COVID-19.

“It is possible to fight more infectious forms like Delta Plus and Delta by combining two different COVID-19 vaccines. However, more data is required before the final approval for the combination of the two vaccines can be given,” Dr Guleria told NDTV.

“Early studies indicate that combining two different shots may be an option. We need to study which of the two vaccines can be combined for effective results. But of course, this may affect the effectiveness of the vaccine.” may increase,” he said.

Last month, the Center announced that as part of its new immunization policy, government experts will examine different combinations of COVID-19 vaccine doses to see if they can improve efficacy.

Dr. Guleria also disregarded the concern that vaccination against the Delta Plus strain would be ineffective. The AIIMS director said additional data was needed to determine whether the mutated strain was capable of rendering vaccination ineffective.

A mutation of the delta plus delta variation, or B.1.617.2 strain, was initially discovered in India and is believed to be responsible for the devastating second wave that hit the country in April–May. Many experts have speculated that the Delta Plus variant could trigger a third wave in the near future, while top doctors have said that a potential third wave would be unlikely to be as devastating as the second.

Dr. Guleria also said that if someone has received both doses of the vaccine, but is still exposed to the virus, he may get the disease, but it will only be “mild”.

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